In October 2012, Robert J. Lefkowitz, MD, James B. Duke Professor of Medicine (Cardiology), was awarded the Nobel Prize in Chemistry 2012 for his research of G-protein-coupled receptors at Duke over 39 years. Read more about Lefkowitz's Nobel year.
Basic research initiatives within the Duke Division of Cardiology include the following:
Investigations of the molecular mechanisms that play a role in heart disease, as well as efforts to develop genomic predictors and to incorporate genomic tools into clinical decision-making
- Physiologic Regulation of Gene Expression and Metabolic Capacity in Skeletal Muscle
- The AGENDA Project
Initiatives exploring the basic biological processes that contribute to vascular disease
Studies of the biochemical mechanisms and properties that underlie normal cardiovascular function as well as diseases such as heart failure
Investigating the molecular and signaling mechanisms behind angiogenesis, vascular remodeling, and heart failure
Clarifying the basic mechanisms that underlie excitation in cardiac muscle in both normal heart function and arrhythmias
At the Duke Cardiovascular Magnetic Resonance Center, we are interested in understanding the mechanisms of cardiovascular disease and translating that knowledge into more sensitive and specific cardiovascular imaging. Learn more.