Mandel Awards

2018 Mandel Foundation Scholar, Seed Grant and Fellowship Awardees

Awardees Title Award
Sudarshan Rajagopal

Defining a Role for Beta-Arrestin-mediated VEGF Signaling in Cardiovascular Disease

Mandel Scholar
Jingli Cao

Dissecting the mechanisms of epicardium-mediated heart regeneration

Mandel Fellow
Ravi Karra Genome-editing approaches for restoring regenerative capacity to the mammalian heart Mandel Seed
Alexander Grabner The role of FGF23 and FGFR4 in cardio-renal syndrome Mandel Seed
Jonathan Stiber Anti-Atherogenic Mechanisms of Drebrin Mandel Seed

2017 Mandel Foundation Scholar, Seed Grant and Fellowship Awardees

Awardees Title Award
Ravi Karra Reprogramming Regenerative Capacity to the Mammalian Heart Mandel Scholar
Han Kyu Lee Cerebrovascular Infarction (Stroke) in an Animal Model Mandel Fellow
Dennis Abraham Protecting Cardiac Function by Harnessing the Fibroblast Secretome Mandel Seed
Neil Freedman Molecular Mechanisms of Arteriovenous Fistula Maturation and Failure Mandel Seed
Robert McGarrah The Role of the Nuclear Receptor, RORα, in Myocardial Metabolism Mandel Seed

2016 Mandel Foundation Seed Grant and Fellowship Awardees

Awardees Title
Ravi Karra Genetic Approaches to Dissect Modes of Cardiac Growth in the Mammalian Heart
Christopher Holley Regulation of oxidative stress by snoRNAs in hypertensive heart disease
Mary Hutson Regulation of Developmental Cardiac Hypertrophy Using Radiofrequency Controlled TRP Channels
Nathan Rudemiller Mandel Fellowship

2015 Mandel Foundation Seed Grant and Fellowship Awardees

Awardees Title
Paul Rosenberg/Elizabeth Finch STIM-1 dependent calcium signaling in neuronal responses to hypoxia and ischemia
Neil Freedman/Susan Gurley Chronic Kidney Disease Potentiates Vein Graft Disease: Cytokine-based Mechanisms
Deepak Voora/Rima Kaddurah-Daouk Pharmacometabaiomic profiling of simvastatin-induced adverse events
Robert Lefkowitz Molecular Mechanisms of Biased Agonism at the Angiotensin Receptor
Stacy Johnson The Role of Podocyte AT1 Receptor in Hypertensive Kidney Disease

2014 Mandel Foundation Seed Grant and Fellowship Awardees

Awardees Title
Dennis Abraham TREK-1 inhibition as novel therapy for treating diastolic dysfunction
Neil Freedman Chronic Kidney Disease Potentiates Vein Graft Disease: Cytokine-based Mechanisms
Christopher Kontos Regulation of endothelial inflammation and atherosclerosis by Caskin2, a novel Tie1-interacting protein
Robert Lefkowitz Molecular Mechanisms of Biased Agonism at the Angiotensin Receptor
Jiandong Zhang Tissue-dependent Activation of Interleukin 1 Receptor Contributes to the Development of Hypertension

2013 Mandel Foundation Seed Grant and Fellowship Awardees

Awardees Title
Jonathan Stiber/Neil Freedman/Steven Crowley Role of Drebrin in Vascular Smooth Muscle Remodeling
Geoffrey Pitt Multilevel investigations into a human CaV1.2-dependent arrhythmogenic disorder
Matthew Wolf Mechanisms underlying cardiomyocyte growth decisions: proliferation vs. hypertrophy
Sudha Shenoy/Matthew Sparks Roles of the deubiquitinase USP20 in AT1R signaling: impact on vasoconstriction and hypertension
Yen Rei Yu-Fellow  

2012 Mandel Foundation Seed Grant and Fellowship Awardees

Awardees Title
Ken Poss Cardiomyocyte-Specific Expression Profiling of Scarring Versus Regeneration
Paul Rosenberg/Maria Mirotsou Functional Characterization of MicroRNA-mediated in vitro and in vivo Direct Reprogramming of Fibroblasts to Cardiomyocytes
Jonathan Stiber/Neil Freedman/Steven Crowley Role of Drebrin in Vascular Smooth Muscle Remodeling
Nenad Bursac/Howard Rockman Cardiomyocyte-Fibroblast Interactions in 3-D Engineered Cardiac Tissues

2011-12 CVRC Collaborative Project Initiative Awardees

Awardees Title
Nenad Bursac/Howard Rockman Role of Cell Fusion in Reprogramming Human MSCs into Cells with a Functional Cardiac Phenotype
Sudha Shenoy/Neil Freedman Regulation of Vascular Smooth Muscle B-arrestin2 by USP20
Howard Rockman/Robert Lefkowitz/Mary Hutson The role of B-arrestin in aortic aneurysm formation in Marfan's Syndrome
Ken Poss/Nico Katsanis Epigenetic Regulation of Cardiac Regeneration
Blanche Capel/Michael Gunn Genetic Regulation of Critical Limb Ischemia
Christopher Kontos/Nicholas Katsanis Regulation of the spermatogonial stem cell niche by testicular macrophages
Michelle Winn/Laura Svetkey/Uptel Patel/Christopher Newgard/Beth Hauser/Svati Shah/David Goldstein Determinants and predictors of progressive kidney disease in African Americans
Matthew Hirschey/Deborah Muoio Comprehensive survey of nutrient-induced regulation of mitochondrial protein acetylation
Jonathan Stiber/Neil Freedman Role of Drebrin in Vascular Smooth Muscle Remodeling
Kent Nilsson/Nenad Bursac/Vann Bennett Optical Mapping as a Method for Understanding Ankyrin Function in the Heart